a way of showing interactions between proteins, domains, and peptides, and the affinity of the interactions

a threshold KD value used to identify interactions above a certain strength

the group of proteins expressed in a specific part of the cell (such as mitochondria, …)

peroxidase enzyme catalysing the oxidation of phenol derivatives to phenoxy radicals, used to add biotin to nearby proteins

analytical technique used to identify specific proteins in tissue homogenate or extract; also allows visualisation, distinguishing, and quantification of different protein in complex protein solutions

mass spectrometry technique fragmenting individual ions from the first stage of mass spectrometry, detecting the mass/charge ratio of smaller ions after the fragmentation step; used for quantitative proteomics

a measurable indicator of a biological state, such as disease; can be used to determine therapeutic interventions

a method to discover biomarkers in vivo, allowing cells, tissue, and blood plasma to be studied with label-free mass-spectrometry quantitation

proteins containing an oligosaccharide covalently attached to amino acid side chains through post-translational modification

process analysing a preselected group of proteins, such as biomarker panels in cancer progression